Carbamic acid, N-[(1S)-1-[[[(1S)-3-(cyclopropylamino)-2,3-dioxo-1-(phenylmethyl)propyl]amino]carbonyl]-3-methylbutyl]-, 2-(2-methoxyethoxy)ethyl ester
SNJ-1945
CAS: 854402-59-8
Molecular Formula: C25 H37 N3 O7
Carbamic acid, N-[(1S)-1-[[[(1S)-3-(cyclopropylamino)-2,3-dioxo-1-(phenylmethyl)propyl]amino]carbonyl]-3-methylbutyl]-, 2-(2-methoxyethoxy)ethyl ester - Names and Identifiers
| Name | SNJ-1945 |
| Synonyms | SNJ-1945 Carbamic acid, N-[(1S)-1-[[[(1S)-3-(cyclopropylamino)-2,3-dioxo-1-(phenylmethyl)propyl]amino]carbonyl]-3-methylbutyl]-, 2-(2-methoxyethoxy)ethyl ester |
| CAS | 854402-59-8 |
Carbamic acid, N-[(1S)-1-[[[(1S)-3-(cyclopropylamino)-2,3-dioxo-1-(phenylmethyl)propyl]amino]carbonyl]-3-methylbutyl]-, 2-(2-methoxyethoxy)ethyl ester - Physico-chemical Properties
| Molecular Formula | C25 H37 N3 O7 |
| Molar Mass | 491.58 |
Carbamic acid, N-[(1S)-1-[[[(1S)-3-(cyclopropylamino)-2,3-dioxo-1-(phenylmethyl)propyl]amino]carbonyl]-3-methylbutyl]-, 2-(2-methoxyethoxy)ethyl ester - Reference Information
| introduction | SNJ-1945 is a calpain inhibitor with better retinal permeability, high oral bioavailability and long half-life. SNJ1945 saved the defective function of anencephaly. SNJ-1945 protect SH-SY5Y cells from MPP() and rotenone. SNJ-1945 reduce mouse retinal cell death in vitro and in vivo. SNJ-1945 has good water solubility and can prevent the heart from KCl sudden arrest and reperfusion injury associated with impaired total Ca(2 +) treatment by inhibiting the proteolysis of α-fodrin as cardioplegia. |
Last Update：2024-04-09 15:16:41
![Carbamic acid, N-[(1S)-1-[[[(1S)-3-(cyclopropylamino)-2,3-dioxo-1-(phenylmethyl)propyl]amino]carbonyl]-3-methylbutyl]-, 2-(2-methoxyethoxy)ethyl ester](http://res.chembk.com/assets/images/structure/854402-59-8.gif)